A Comparative Study of Oxidative Stress and Antioxidants Levels in Preterm and Term Infants and Their Mothers
نویسنده
چکیده
Free radical injury is thought to be one of the common mechanisms for several diseases in preterm infants. Lipid peroxidation plays a vital role in the pathogenesis of many neonatal complications because the antioxidant system of preterm infants is highly stressed and incompletely developed. We aimed to determine the oxidative stress [Malondialdehyde (MDA)] and antioxidants [Total antioxidant activity (TAA) and Vitamin E] in cord blood of preterm (n=20) and term infants (n=20) and in the blood of their mothers. In preterm infants and their mothers TAA and Vitamin E levels were low as compared to term infants and their mothers. In preterm infants and their mothers MDA was high as compared to term infants and their mothers. Therefore it is possible to postulate that preterm infants and their mothers are more susceptible to oxidative stress than term infants and their mothers.
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